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- Camilla Belle as Rose Slavin
- Daniel Day-Lewis as Jack Slavin
- Catherine Keener as Kathleen
- Ryan McDonald as Rodney
- Paul Dano as Thaddius
- Jason Lee as Gray
- Jena Malone as Red Berry
- Beau Bridges as Marty Rance
- Susanna Thompson as Miriam Rance
- Lily Balderston as Baby Rose Slavin
- Nicole Balderston as Virginia