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- Toni Collette as Iris Chapman
- Parker Posey as Margaret Burre
- Lisa Kudrow as Paula
- Alanna Ubach as Jane
- Helen FitzGerald as Cleo
- Stanley DeSantis as Art
- Jamie Kennedy as Eddie
- David James Elliott as Mr. MacNamee
- Debra Jo Rupp as Barbara
- Kevin Cooney as Mr. Kilmer
- Bob Balaban as Milton Lasky
- Paul Dooley as Bud Chapman
- Scott Mosenson as Jack Shoberg