Horrific burn victim and scientist Peyton Westlake continues to lurk the city as the mysterious figure of Darkman; ripping off gangsters and criminals for their money. Using these illegal funds, he seeks to crack his photoreactive synthetic skin's limitation of breaking down after 100 minutes.
Westlake is thrilled to find that another scientist, Dr. Brinkman is working on his own synthetic skin formula which may hold the key to cracking his 100 minute limit and makes contact with Brinkman. The two scientists agree to collaborate when their work is interrupted by the return of an old nemesis from Darkman's past, Robert G. Durant!
- Larry Drake as Robert G. Durant
- Arnold Vosloo as Darkman
- Kim Delaney as Jill Randall
- Renee O'Connor as Laurie Brinkman
- Lawrence Dane as Dr. Alfred Hathaway
- Jesse Collins as Dr. David Brinkman
- David Ferry as Eddie
- Rod Wilson as Ivan Druganov
- Jack Langedijk as Rollo Latham