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- Andy Serkis as Dr. Adrian King
- Thomas Brodie-Sangster as Donald Clarke
- Sharon Horgan as Renata Clarke
- Aisling Loftus as Shelly
- Michael McElhatton as James Clarke
- Jessica Schwarz as Tanya
- Ben Harding as Michael
- Killian Coyle as Hugo
- Ronan Raftery as Jeff
- Jane Brennan as Dr. Rebecca Johnston