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- Peter Graves as Dr. Paul Nelson
- Lee Van Cleef as Dr. Tom Anderson
- Beverly Garland as Claire Anderson
- Sally Fraser as Joan Nelson
- Russ Bender as General James Pattick
- Taggart Casey as Sheriff N.J. Shallert
- Karen Kadler as Dr. Ellen Peters
- Dick Miller as First Sergeant
- Jonathan Haze as Corporal Manuel Ortiz
- Paul Harbor as Dr. Floyd Mason
- Charles B. Griffith as Dr. Pete Shelton
- Thomas E. Jackson as George Haskell