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- Johnny Knoxville as Irving Zisman
- Jackson Nicoll as Billy
- Greg Harris as Chuck
- Georgina Cates as Kimmie
- Kamber Hejlik as Doctor
- Jill Kill as Pageant Reporter
- Madison Davis as Juggalo Girl
- George Faughnan as Juggalo Guy
- Grasie Mercedes as Hostess
- Marilynn Allain as Receptionist
- Jack Polick as Funeral Worker
- Spike Jonze as Gloria
- Catherine Keener as Ellie