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- John Lithgow as Dr. Carter Nix
- Lolita Davidovich as Jenny Nix
- Steven Bauer as Jack Dante
- Frances Sternhagen as Dr Lynn Waldheim
- Gregg Henry as Lieutenant Terri
- Tom Bower as Sergeant Cully
- Mel Harris as Sarah
- Teri Austin as Karen
- Gabrielle Carteris as Nan
- Barton Heyman as Mack
- Amanda Pombo as Amy
- Kathleen Callan as Emma