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- Ellen Burstyn as Hagar Shipley
- Christine Horne as Young Hagar
- Samantha Weinstein as Young Hagar
- Dylan Baker as Marvin
- Sheila McCarthy as Doris
- Kevin Zegers as John
- Ellen Page as Arlene
- Josette Halpert as Young Arlene
- Wings Hauser as Older Bram
- Cole Hauser as Young Bram
- Aaron Ashmore as Matt
- Connor Price as Young Matt
- Luke Kirby as Leo